Onset of protection from experimental infection with type 2 bovine viral diarrhea virus following vaccination with a modified-live vaccine.
نویسندگان
چکیده
The onset of protection after the administration of a modified-live bovine viral diarrhea virus (BVDV) vaccine was determined. Protection was determined following experimental infection with a virulent type-2 BVDV (strain 1373) in cattle vaccinated 3, 5, or 7 days before BVDV infection. Protection, as measured by reduced virus shedding, lack of leukopenia, reduction in viremia, and reduced mortality, was present as early as 3 days after vaccination with a single dose of modified-live BVDV vaccine. Complete protection was obtained in cattle vaccinated 5 or 7 days before BVDV experimental infection.
منابع مشابه
Evaluation of fetal protection against experimental infection with type 1 and type 2 bovine viral diarrhea virus after vaccination of the dam with a bivalent modified-live virus vaccine.
OBJECTIVE To evaluate the efficacy of a modified-live virus (MLV) combination vaccine containing type 1 and type 2 bovine viral diarrhea virus (BVDV) in providing fetal protection against challenge with heterologous type 1 and type 2 BVDV. DESIGN Prospective study. ANIMALS 55 heifers. PROCEDURE Heifers were vaccinated with a commercial MLV combination vaccine or given a sham vaccine (ster...
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ورودعنوان ژورنال:
- Veterinary therapeutics : research in applied veterinary medicine
دوره 8 1 شماره
صفحات -
تاریخ انتشار 2007